Petr Pachl - Concepedia

Author

Petr Pachl

Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry ORCID

Also Known As

J. Brynda, P. Pachl, Petr Pachl

Publications

724

Citations

H-Index

Concepts

All Affiliations

Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry Czech Academy of Sciences Czech Academy of Sciences, Institute of Molecular Genetics Charles University Czech Academy of Sciences, Institute of Microbiology

About

Petr Pachl is an author at Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry specializing in medicine, natural sciences, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	9	9	315
2	Natural Sciences	7	7	262
3	Biochemistry	6	6	239
4	Cell Biology	2	2	51
5	Health Sciences	1	1	27

Petr Pachl

Publications

630

Citations

H-Index

Page 1

	Year	Citations
Metallacarborane Sulfamides: Unconventional, Specific, and Highly Selective Inhibitors of Carbonic Anhydrase IX Bohumı́r Grüner, J. Brynda, Viswanath Das, Journal of Medicinal Chemistry Combinatorial ChemistryOrganic ChemistryChemistryPharmaceutical ChemistryTumor Biology	2019	80
Rational design of urea-based glutamate carboxypeptidase II (GCPII) inhibitors as versatile tools for specific drug targeting and delivery Jan Tykvart, Jiří Schimer, Jitka Bařinková, Bioorganic & Medicinal Chemistry Specific Drug TargetingMedicinal ChemistryVersatile ToolsBiochemistryG Protein-coupled Receptor	2014	58
General and Modular Strategy for Designing Potent, Selective, and Pharmacologically Compliant Inhibitors of Rhomboid Proteases Anežka Tichá, Stancho Stanchev, Kutti R. Vinothkumar, Cell chemical biology	2017	53
Structural Basis for the Interaction Between Carbonic Anhydrase and 1,2,3,4-tetrahydroisoquinolin-2-ylsulfonamides P. Mäder, J. Brynda, Rosaria Gitto, Journal of Medicinal Chemistry Crystal StructureOrganic ChemistryPharmacotherapyChemistryHeterocycle Chemistry	2011	38
Structures and kinetics of Thermotoga maritima MetY reveal new insights into the predominant sulfurylation enzyme of bacterial methionine biosynthesis Jodi L. Brewster, Petr Pachl, James L. O. McKellar, Journal of Biological Chemistry	2021	35
Kinetic, Thermodynamic, and Structural Analysis of Drug Resistance Mutations in Neuraminidase from the 2009 Pandemic Influenza Virus Jana Pokorná, Petr Pachl, Elena Karlukova, Viruses Virus StructureDrug Resistance AnalysisDrug Resistance MutationsPandemic Influenza VirusAntiviral Drug Development	2018	29
Triggering HIV polyprotein processing by light using rapid photodegradation of a tight-binding protease inhibitor Jiří Schimer, Marcela Pávová, Maria Anders, Nature Communications	2015	28
Crystal structure of native α-<scp>L</scp>-rhamnosidase from <i>Aspergillus terreus</i> Petr Pachl, Jana Škerlová, Daniela Šimčíková, Acta Crystallographica Section D Structural Biology Crystal StructureBiosynthesisBiochemistryNatural SciencesBiocatalysis	2018	27
3,5,7-Substituted Pyrazolo[4,3-<i>d</i>]pyrimidine Inhibitors of Cyclin-Dependent Kinases and Their Evaluation in Lymphoma Models Radek Jorda, Libor Havlı́ček, Antonín Šturc, Journal of Medicinal Chemistry	2019	27
Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation Aleš Hnı́zda, Milan Fábry, Takaya Moriyama, Leukemia Hematological MalignancySystems BiologyMixed-phenotype Acute LeukemiaMalignant Blood DisorderHematology	2018	27

Page 1