Petr Pachl

Metallacarborane Sulfamides: Unconventional, Specific, and Highly Selective Inhibitors of Carbonic Anhydrase IX

Bohumı́r Grüner, J. Brynda, Viswanath Das et al. · Journal of Medicinal Chemistry · 2019 · 80 citations

Combinatorial Chemistry, Organic Chemistry, Chemistry +16

Rational design of urea-based glutamate carboxypeptidase II (GCPII) inhibitors as versatile tools for specific drug targeting and delivery

Jan Tykvart, Jiří Schimer, Jitka Bařinková et al. · Bioorganic & Medicinal Chemistry · 2014 · 58 citations · Full text

Specific Drug Targeting, Medicinal Chemistry, Versatile Tools +10

General and Modular Strategy for Designing Potent, Selective, and Pharmacologically Compliant Inhibitors of Rhomboid Proteases

Anežka Tichá, Stancho Stanchev, Kutti R. Vinothkumar et al. · Cell chemical biology · 2017 · 53 citations · Full text

Structural Basis for the Interaction Between Carbonic Anhydrase and 1,2,3,4-tetrahydroisoquinolin-2-ylsulfonamides

P. Mäder, J. Brynda, Rosaria Gitto et al. · Journal of Medicinal Chemistry · 2011 · 38 citations · Full text

Crystal Structure, Organic Chemistry, Pharmacotherapy +19

Structures and kinetics of Thermotoga maritima MetY reveal new insights into the predominant sulfurylation enzyme of bacterial methionine biosynthesis

Jodi L. Brewster, Petr Pachl, James L. O. McKellar et al. · Journal of Biological Chemistry · 2021 · 35 citations · Full text