J. Brynda

From nonpeptide toward noncarbon protease inhibitors: Metallacarboranes as specific and potent inhibitors of HIV protease

Petr Cígler, Milan Kožíšek, Pavlína Řezáčová et al. · Proceedings of the National Academy of Sciences · 2005 · 307 citations · Full text

Design of HIV Protease Inhibitors Based on Inorganic Polyhedral Metallacarboranes

Pavlína Řezáčová, Jana Pokorná, J. Brynda et al. · Journal of Medicinal Chemistry · 2009 · 149 citations

Inorganic Polyhedral Metallacarborane Inhibitors of HIV Protease: A New Approach to Overcoming Antiviral Resistance

Milan Kožíšek, Petr Cígler, Martin Lepšı́k et al. · Journal of Medicinal Chemistry · 2008 · 107 citations · Full text

Antiviral Drug, Chemical Biology, Overcoming Antiviral Resistance +19

Carborane‐Based Carbonic Anhydrase Inhibitors

J. Brynda, P. Mäder, Václav Šícha et al. · Angewandte Chemie International Edition · 2013 · 102 citations

Molecular Analysis of the HIV-1 Resistance Development: Enzymatic Activities, Crystal Structures, and Thermodynamics of Nelfinavir-resistant HIV Protease Mutants

Milan Kožíšek, Jenelle K. Bray, Pavlína Řezáčová et al. · Journal of Molecular Biology · 2007 · 87 citations

Virus Structure, Biochemistry, Protein Folding +11