Salvatore Avolio

Potent Inhibitors of Subgenomic Hepatitis C Virus RNA Replication through Optimization of Indole-<i>N</i>-Acetamide Allosteric Inhibitors of the Viral NS5B Polymerase

Steven J. Harper, Salvatore Avolio, Barbara Pacini et al. · Journal of Medicinal Chemistry · 2005 · 86 citations · Full text

Crystal Structure, Viral Replication, Viral Polymerase Structure +21

Development and Preliminary Optimization of Indole-<i>N</i>-Acetamide Inhibitors of Hepatitis C Virus NS5B Polymerase

Steven J. Harper, Barbara Pacini, Salvatore Avolio et al. · Journal of Medicinal Chemistry · 2005 · 84 citations · Full text

Viral Replication, Allosteric Inhibition, Viral Polymerase Structure +18

Active site inhibitors of HCV NS5B polymerase. The development and pharmacophore of 2-thienyl-5,6-dihydroxypyrimidine-4-carboxylic acid

Ian Stansfield, Salvatore Avolio, Stefania Colarusso et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 41 citations · Full text

Hcv Ns5b Polymerase, Active Site Inhibitors, Biochemistry +10

Synthesis and antiviral properties of novel 7-heterocyclic substituted 7-deaza-adenine nucleoside inhibitors of Hepatitis C NS5B polymerase

Maria Emilia Di Francesco, Salvatore Avolio, Marco Pompei et al. · Bioorganic & Medicinal Chemistry · 2012 · 30 citations

Biochemistry, Medicine, Antiviral Drug Development +7

Inhibitors of hepatitis C virus NS3/4A: α-Ketoamide based macrocyclic inhibitors

Salvatore Avolio, Keith D. Robertson, José Ignacio Martı́n Hernando et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 19 citations

Macrocyclic Inhibitors, Viral Hepatitis, Medicine +8