Ta‐Hsiang Chao

A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib

Dharminder Chauhan, Laurence Catley, Guilan Li et al. · Cancer Cell · 2005 · 695 citations · Full text

Hematological Malignancy, Medicine, Apoptosis +9

Structure−Activity Relationship Studies of Salinosporamide A (NPI-0052), a Novel Marine Derived Proteasome Inhibitor

Venkat R. Macherla, Scott S. Mitchell, Rama Rao Manam et al. · Journal of Medicinal Chemistry · 2005 · 235 citations

Proteasome Inhibition, Medicinal Chemistry, Pharmaceutical Chemistry +14

Salinosporamide A (NPI-0052) potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through down-modulation of NF-κB–regulated gene products

Kwang Seok Ahn, Gautam Sethi, Ta‐Hsiang Chao et al. · Blood · 2007 · 121 citations · Full text

NPI-0052 Enhances Tumoricidal Response to Conventional Cancer Therapy in a Colon Cancer Model

James C. Cusack, Rong Liu, Lijun Xia et al. · Clinical Cancer Research · 2006 · 91 citations

Salinosporamides D−J from the Marine Actinomycete <i>Salinispora tropica</i>, Bromosalinosporamide, and Thioester Derivatives Are Potent Inhibitors of the 20S Proteasome

Katherine A. Reed, Rama Rao Manam, Scott S. Mitchell et al. · Journal of Natural Products · 2007 · 87 citations

Salinosporamides F, Medicinal Chemistry, Marine Biotechnology +15