21:I[432972,["/_next/static/chunks/bb923814e1f4d2e9.js","/_next/static/chunks/dd3ee9f5b7716ca6.js","/_next/static/chunks/4204a0ae82542ca8.js","/_next/static/chunks/1270dead247da766.js","/_next/static/chunks/6e1aa89a642f40be.js","/_next/static/chunks/2d7aa753e81324a8.js","/_next/static/chunks/8ffd0b71567920d8.js","/_next/static/chunks/67ea6dfd21f16c5f.js","/_next/static/chunks/24eb4379f68013fd.js","/_next/static/chunks/b8cd775ffdf935bd.js","/_next/static/chunks/983103cd9eb7b428.js","/_next/static/chunks/263f2cdcb9aa2341.js","/_next/static/chunks/294b9525248c8e5f.js"],"default"] 22:T4d7,Hydrogen sulfide (H₂S) is an important signaling molecule related to many diseases. Thus, H₂S has a great impact on the pathological and physiological processes in biological systems. Cysteine (l-Cys) is a building block for proteins and important metabolites. To understand their roles in the physiological metabolic procedures, the measurement of the H₂S level and identifying cysteine in the biological system is significant. In this study, through the functionalization of UiO-66-NH₂ by 4-(2,2-dicyanoethenyl)benzoic acid (BQB), a novel UiO-66-NH-BQB is successfully synthesized and used as a fluorescence probe to recognize and detect H₂S and l-Cys. The fluorescence signals of the probe are enhanced great when it is exposed to H₂S or cysteine molecules; thus, it is able to determine quantificationally the H₂S concentration in an aqueous solution. The detection limitation of the UiO-66-NH-BQB to H₂S concentration is found to be as low as 1.74 μM. The developed fluorescent probe based on UiO-66-NH-BQB displays a high selectivity and excellent biocompatibility, which is very promising for recognition and sensing of biothiols in organisms.

#	Concept	H-Index	Publications	Citations
1	Biochemistry	2	2	166
2	Engineering	1	1	36
3	Medicine	1	1	130
4	Natural Sciences	1	1	36
5	Chemistry	1	1	36

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