Larry V. Pearce

Molecular Determinants of Vanilloid Sensitivity in TRPV1

Narender R. Gavva, Lana Klionsky, Yusheng Qu et al. · Journal of Biological Chemistry · 2004 · 355 citations · Full text

<i>N</i>-(3-Acyloxy-2-benzylpropyl)-<i>N</i>‘-[4-(methylsulfonylamino)benzyl]thiourea Analogues:  Novel Potent and High Affinity Antagonists and Partial Antagonists of the Vanilloid Receptor

Jeewoo Lee, Jiyoun Lee, Myungshim Kang et al. · Journal of Medicinal Chemistry · 2003 · 108 citations · Full text

Structural Insight into Tetrameric hTRPV1 from Homology Modeling, Molecular Docking, Molecular Dynamics Simulation, Virtual Screening, and Bioassay Validations

Zhiwei Feng, Larry V. Pearce, Xiaomeng Xu et al. · Journal of Chemical Information and Modeling · 2015 · 74 citations

Engineering, Structural Bioinformatics, Biomolecular Structure Prediction +18

Structural insights into transient receptor potential vanilloid type 1 (TRPV1) from homology modeling, flexible docking, and mutational studies

Jin Hee Lee, Yoonji Lee, HyungChul Ryu et al. · Journal of Computer-Aided Molecular Design · 2011 · 71 citations · Full text

Signal Transduction, G Protein-coupled Receptor, Flexible Docking +10

Evodiamine functions as an agonist for the vanilloid receptor TRPV1

Larry V. Pearce, Pavel A. Petukhov, Tamás Szabó et al. · Organic & Biomolecular Chemistry · 2004 · 67 citations

Molecular Biology, Evodiamine Functions, Pharmacotherapy +18