Xiaomeng Xu

APL-1, a <i>Caenorhabditis elegans</i> protein related to the human β-amyloid precursor protein, is essential for viability

Angela Hornsten, Jason G. Lieberthal, Shruti Fadia et al. · Proceedings of the National Academy of Sciences · 2007 · 145 citations · Full text

Life Sciences, Developmental Biology, Molecular Biology +11

Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into mechanisms of G protein selectivity

Jesse I. Mobbs, Matthew J. Belousoff, Kaleeckal G. Harikumar et al. · PLoS Biology · 2021 · 88 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Structural Insight into Tetrameric hTRPV1 from Homology Modeling, Molecular Docking, Molecular Dynamics Simulation, Virtual Screening, and Bioassay Validations

Zhiwei Feng, Larry V. Pearce, Xiaomeng Xu et al. · Journal of Chemical Information and Modeling · 2015 · 75 citations

Pharmacy, Molecular Biology, Pharmacology +17

Structural Characterization of the E2 Domain of APL-1, a Caenorhabditis elegans Homolog of Human Amyloid Precursor Protein, and Its Heparin Binding Site

J. Todd Hoopes, Xuying Liu, Xiaomeng Xu et al. · Journal of Biological Chemistry · 2009 · 22 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Chemogenomics knowledgebase and systems pharmacology for hallucinogen target identification—Salvinorin A as a case study

Xiaomeng Xu, Shifan Ma, Zhiwei Feng et al. · Journal of Molecular Graphics and Modelling · 2016 · 19 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16