Ruth R. Wexler

Identification of angiotensin II receptor subtypes

Andrew T. Chiu, William F. Herblin, Dale E. McCall et al. · Biochemical and Biophysical Research Communications · 1989 · 822 citations

Hypertension, Molecular Physiology, Autoimmune Disease +6

MEK inhibitors: The chemistry and biological activity of U0126, its analogs, and cyclization products

John V. Duncia, Joseph B. Santella, C. Anne Higley et al. · Bioorganic & Medicinal Chemistry Letters · 1998 · 404 citations · Full text

Biological Activity, Mek Inhibitors, Medicinal Chemistry +12

Discovery of 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro- 1<i>H</i>-pyrazolo[3,4-<i>c</i>]pyridine-3-carboxamide (Apixaban, BMS-562247), a Highly Potent, Selective, Efficacious, and Orally Bioavailable Inhibitor of Blood Coagulation Factor Xa

Donald Pinto, Michael J. Orwat, Stephanie C. Koch et al. · Journal of Medicinal Chemistry · 2007 · 391 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Primary Aniline +15

Nonpeptide angiotensin II receptor antagonists. XI. Pharmacology of EXP3174: an active metabolite of DuP 753, an orally active antihypertensive agent.

Pancras C. Wong, William A. Price, Andrew T. Chiu et al. · Journal of Pharmacology and Experimental Therapeutics · 1990 · 330 citations

Nonpeptide angiotensin II receptor antagonists. VII. Cellular and biochemical pharmacology of DuP 753, an orally active antihypertensive agent.

Andrew T. Chiu, Dale E. McCall, William A. Price et al. · Journal of Pharmacology and Experimental Therapeutics · 1990 · 317 citations