Alessandra Boletta

Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

Kazushige Hanaoka, Feng Qian, Alessandra Boletta et al. · Nature · 2000 · 808 citations

Biophysics, Chemistry, Molecular Engineering +1

Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy

Isaline Rowe, Marco Chiaravalli, Valeria Mannella et al. · Nature Medicine · 2013 · 478 citations · Full text

Metabolic Syndrome, Renal Function, Renal Disease +14

PKD1 Induces p21waf1 and Regulation of the Cell Cycle via Direct Activation of the JAK-STAT Signaling Pathway in a Process Requiring PKD2

Anil K. Bhunia, Klaus Piontek, Alessandra Boletta et al. · Cell · 2002 · 446 citations · Full text

Signal Transduction, Signaling Pathway, Cell Division +10

Cleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by human autosomal-dominant polycystic kidney disease 1-associated mutations

Feng Qian, Alessandra Boletta, Anil K. Bhunia et al. · Proceedings of the National Academy of Sciences · 2002 · 325 citations · Full text

Polycystin-1, the Gene Product of PKD1, Induces Resistance to Apoptosis and Spontaneous Tubulogenesis in MDCK Cells

Alessandra Boletta, Feng Qian, Luiz F. Onuchic et al. · Molecular Cell · 2000 · 222 citations · Full text