Concepedia

Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy

Isaline Rowe, Marco Chiaravalli, Valeria Mannella, Valeria Ulisse, Giacomo Quilici, Monika Pema, Xuewen Song, Hangxue Xu, Silvia Mari, Feng Qian,

Nature Medicine · 2013 · 494 citations · 25 references

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25

Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1

Katrin Düvel, Jessica L. Yecies, Suchithra Menon et al. · Molecular Cell · 2010 · 2K citations · Full text

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The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease

Jonathan M. Shillingford, Noel Murcia, Claire H. Larson et al. · Proceedings of the National Academy of Sciences · 2006 · 798 citations · Full text

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Everolimus in Patients with Autosomal Dominant Polycystic Kidney Disease

Gerd Walz, Klemens Budde, Marwan Mannaa et al. · New England Journal of Medicine · 2010 · 577 citations · Full text

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Sirolimus and Kidney Growth in Autosomal Dominant Polycystic Kidney Disease

Andreas L. Serra, Diane Poster, Andreas D. Kistler et al. · New England Journal of Medicine · 2010 · 563 citations · Full text

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Oncogenic B-RAF Negatively Regulates the Tumor Suppressor LKB1 to Promote Melanoma Cell Proliferation

Bin Zheng, Joseph H. Jeong, John M. Asara et al. · Molecular Cell · 2009 · 354 citations · Full text

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