Tingjin Sherryl Soh

A Crystal Structure of the Dengue Virus NS5 Protein Reveals a Novel Inter-domain Interface Essential for Protein Flexibility and Virus Replication

Yongqian Zhao, Tingjin Sherryl Soh, Jie Zheng et al. · PLoS Pathogens · 2015 · 256 citations · Full text

Virus Structure, Virus Replication, Crystal Structure +15

Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling

Siew Pheng Lim, Christian G. Noble, Cheah C. Seh et al. · PLoS Pathogens · 2016 · 174 citations · Full text

Viral Replication, Molecular Biology, Antiviral Drug +18

Molecular basis for specific viral RNA recognition and 2′-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5)

Yongqian Zhao, Tingjin Sherryl Soh, Siew Pheng Lim et al. · Proceedings of the National Academy of Sciences · 2015 · 105 citations · Full text

Crystal Structure, Viral Replication, Dengue Virus +18

Flexibility of NS5 Methyltransferase-Polymerase Linker Region Is Essential for Dengue Virus Replication

Yongqian Zhao, Tingjin Sherryl Soh, Kitti Wing Ki Chan et al. · Journal of Virology · 2015 · 50 citations · Full text

Dengue Virus Replication, Viral Replication, Viral Polymerase Mechanism +18

NS5 from Dengue Virus Serotype 2 Can Adopt a Conformation Analogous to That of Its Zika Virus and Japanese Encephalitis Virus Homologues

Abbas El Sahili, Tingjin Sherryl Soh, Jonas Schiltz et al. · Journal of Virology · 2019 · 43 citations · Full text