Santina Acuto

A genetic strategy to treat sickle cell anemia by coregulating globin transgene expression and RNA interference

Selda Samakoglu, Leszek Lisowski, Tülin Budak-Alpdoǧan et al. · Nature Biotechnology · 2005 · 113 citations

Immunohematology, Gene Therapies, Genetic Strategy +11

Lentiviral globin gene therapy with reduced-intensity conditioning in adults with β-thalassemia: a phase 1 trial

Farid Boulad, Aurelio Maggio, Xiuyan Wang et al. · Nature Medicine · 2022 · 45 citations · Full text

Medicine, Phase 1, Hematology +1

Desensitization to hydroxycarbamide following long‐term treatment of thalassaemia intermedia as observed <i>in vivo</i> and in primary erythroid cultures from treated patients

Paolo Rigano, A. Pecoraro, Roberta Calzolari et al. · British Journal of Haematology · 2010 · 43 citations · Full text

Expression of human gamma-globin genes in human erythroleukemia (K562) cells.

M Donovan-Peluso, Santina Acuto, Mark E. Swanson et al. · Journal of Biological Chemistry · 1987 · 25 citations · Full text

βA and βthal DNA haplotypes in Sicily

Aurelio Maggio, Santina Acuto, P. Lo Gioco et al. · Human Genetics · 1986 · 22 citations

Allelic Variant, Haplotype Determination, Genetics +5