Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy

Yang Gao, Naoe Taira Nihira, Xia Bu, +24

Nature Cell Biology

Anti-pd-1 ImmunotherapyCancer ImmunosurveillanceImmunologyTumor ImmunityPd-l1 Nuclear Translocation +8

Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2)

Chao Xu, Chuanbing Bian, Wei Yang, +11

Proceedings of the National Academy of Sciences

Histone ModificationsHistone MarksStructural BioinformaticsEpigenetic ChangeMolecular Regulation +19

Loops Govern SH2 Domain Specificity by Controlling Access to Binding Pockets

Tomonori Kaneko, Haiming Huang, Bing Zhao, +6

Science Signaling

Protein AssemblyMolecular BiologyProtein FoldingSelective BlockageProteomics +15

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins

Rajesh Ghai, Andrea Bugarčić, Huadong Liu, +6

Proceedings of the National Academy of Sciences

Dynamic Methylation of Numb by Set8 Regulates Its Binding to p53 and Apoptosis

Gurpreet K. Dhami, Huadong Liu, Marek Galka, +7

Molecular Cell

Dynamic MethylationSet8 RegulatesEpigenetic ChangeApoptosisEpigenomics +6

A Method for Systematic Mapping of Protein Lysine Methylation Identifies Functions for HP1β in DNA Damage Response

Huadong Liu, Marek Galka, Eiichiro Mori, +11

Molecular Cell

ChromatinSystematic MappingMedicineGeneticsNatural Sciences +9

ERK-mediated phosphorylation regulates SOX10 sumoylation and targets expression in mutant BRAF melanoma

Shujun Han, Yibo Ren, Wangxiao He, +16

Nature Communications

Mutant Braf MelanomaGeneticsAdaptive ResistanceCancer BiologyTumor Biology +15

A new forward kinematic algorithm for a general Stewart platform

Zhou Wanyong, Wuyi Chen, Huadong Liu, +1

Mechanism and Machine Theory

Robot KinematicsTrajectory PlanningGeneral Stewart PlatformEngineeringGuidance System +9

Phosphorylation-dependent substrate selectivity of protein kinase B (AKT1)

Nileeka Balasuriya, Norman E. Davey, Jared L. Johnson, +5

Journal of Biological Chemistry

Prostate-specific oncogene OTUD6A promotes prostatic tumorigenesis via deubiquitinating and stabilizing c-Myc

Yunhua Peng, Jing Liu, Zhen Wang, +13

Cell Death and Differentiation

Prostatic TumorigenesisOncogenic AgentTumor SuppressorProstatic DiseaseRadiation Oncology +5