Andre Shavnya

Palladium‐Catalyzed Synthesis of (Hetero)Aryl Alkyl Sulfones from (Hetero)Aryl Boronic Acids, Unactivated Alkyl Halides, and Potassium Metabisulfite

Andre Shavnya, Kevin D. Hesp, Vincent Mascitti et al. · Angewandte Chemie International Edition · 2015 · 194 citations

Arylboronic Acids, Chemical Engineering, Cross-coupling Reaction +12

Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1<i>H</i>-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of Adenosine Monophosphate-activated Protein Kinase (AMPK), for the Potential Treatment of Diabetic Nephropathy

Kimberly O. Cameron, Daniel W. Kung, Amit S. Kalgutkar et al. · Journal of Medicinal Chemistry · 2016 · 115 citations · Full text

Renal Inflammation, Pharmacotherapy, Insulin Signaling +19

Heterocyclic Allylsulfones as Latent Heteroaryl Nucleophiles in Palladium-Catalyzed Cross-Coupling Reactions

Tim Markovic, Philip R. D. Murray, Benjamin N. Rocke et al. · Journal of the American Chemical Society · 2018 · 108 citations · Full text

Chemical Engineering, Medicinal Chemistry, Engineering +14

Reaction of Alkyl Halides with Rongalite: One-Pot and Telescoped Syntheses of Aliphatic Sulfonamides, Sulfonyl Fluorides, and Unsymmetrical Sulfones

Andre Shavnya, Steven B. Coffey, Kevin D. Hesp et al. · Organic Letters · 2016 · 103 citations

Combinatorial Chemistry, Bioorganic Chemistry, Alkyl Halides +19

Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy

Christopher T. Salatto, Russell Miller, Kimberly O. Cameron et al. · Journal of Pharmacology and Experimental Therapeutics · 2017 · 79 citations · Full text