Eric A. Wold

Discovery of Orally Bioavailable Chromone Derivatives as Potent and Selective BRD4 Inhibitors: Scaffold Hopping, Optimization, and Pharmacological Evaluation

Zhiqing Liu, Haiying Chen, Pingyuan Wang et al. · Journal of Medicinal Chemistry · 2020 · 92 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Discovery, X-ray Crystallography, and Anti-inflammatory Activity of Bromodomain-containing Protein 4 (BRD4) BD1 Inhibitors Targeting a Distinct New Binding Site

Zhiqing Liu, Yi Li, Haiying Chen et al. · Journal of Medicinal Chemistry · 2022 · 52 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Regio- and Stereospecific Synthesis of Oridonin D-Ring Aziridinated Analogues for the Treatment of Triple-Negative Breast Cancer via Mediated Irreversible Covalent Warheads

Ye Ding, Dengfeng Li, Chunyong Ding et al. · Journal of Medicinal Chemistry · 2018 · 44 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Small-Molecule Inhibitors Targeting the Canonical WNT Signaling Pathway for the Treatment of Cancer

Zhiqing Liu, Pingyuan Wang, Eric A. Wold et al. · Journal of Medicinal Chemistry · 2021 · 39 citations · Full text

Medicine, Oncology, Pharmacology +14

Design, Synthesis, and Characterization of 4-Undecylpiperidine-2-carboxamides as Positive Allosteric Modulators of the Serotonin (5-HT) 5-HT_2CReceptor

Christopher Wild, Joanna Miszkiel, Eric A. Wold et al. · Journal of Medicinal Chemistry · 2018 · 36 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17