Christopher Wild

Small Molecule Inhibitors Targeting Activator Protein 1 (AP-1)

Na Ye, Ye Ding, Christopher Wild et al. · Journal of Medicinal Chemistry · 2014 · 299 citations · Full text

Ap-1 Biology, Drug Target, Pivotal Transcription Factor +13

Novel Nitrogen-Enriched Oridonin Analogues with Thiazole-Fused A-Ring: Protecting Group-Free Synthesis, Enhanced Anticancer Profile, and Improved Aqueous Solubility

Chunyong Ding, Yusong Zhang, Haijun Chen et al. · Journal of Medicinal Chemistry · 2013 · 107 citations · Full text

Thiazole-fused A-ring, Medicinal Chemistry, Complex Ent-kaurane Diterpenoid +14

Oridonin Ring A-Based Diverse Constructions of Enone Functionality: Identification of Novel Dienone Analogues Effective for Highly Aggressive Breast Cancer by Inducing Apoptosis

Chunyong Ding, Yusong Zhang, Haijun Chen et al. · Journal of Medicinal Chemistry · 2013 · 78 citations · Full text

Natural Scaffold, Breast Oncology, Cell Death +19

Overcoming Synthetic Challenges of Oridonin A-Ring Structural Diversification: Regio- and Stereoselective Installation of Azides and 1,2,3-Triazoles at the C-1, C-2, or C-3 Position

Chunyong Ding, Yusong Zhang, Haijun Chen et al. · Organic Letters · 2013 · 61 citations

Combinatorial Chemistry, Bioorganic Chemistry, Azide Functionalities +17

Discovery of potent anticancer agent HJC0416, an orally bioavailable small molecule inhibitor of signal transducer and activator of transcription 3 (STAT3)

Haijun Chen, Zhengduo Yang, Chunyong Ding et al. · European Journal of Medicinal Chemistry · 2014 · 53 citations · Full text

Medicinal Chemistry, Drug Targeting, Natural Sciences +10