Activation of the IκB Kinase Complex by TRAF6 Requires a Dimeric Ubiquitin-Conjugating Enzyme Complex and a Unique Polyubiquitin Chain

Li Deng, Chen Wang, Erika Spencer, +6

Cell

Signal TransductionSignaling PathwayCell RegulationIκb Kinase ComplexMolecular Biology +5

Interaction of the Bovine Papillomavirus E2 Protein with Brd4 Tethers the Viral DNA to Host Mitotic Chromosomes

Jianxin You, Jennie L Croyle, Akiko Nishimura, +2

Cell

ChromatinViral DnaVirus StructureViral ReplicationCell Division +12

Identifying the Target Cells and Mechanisms of Merkel Cell Polyomavirus Infection

Wei Liu, Ruifeng Yang, Aimee Payne, +6

Cell Host & Microbe

Molecular VirologyTarget CellsPathogenesisViral PathogenesisImmunology +4

Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Interacts with Bromodomain Protein Brd4 on Host Mitotic Chromosomes

Jianxin You, Viswanathan Srinivasan, Gerald V. Denis, +4

Journal of Virology

Bromodomain Protein Brd4 Associated with Acetylated Chromatin Is Important for Maintenance of Higher-order Chromatin Structure

Ranran Wang, Qing Li, Christine M. Helfer, +2

Journal of Biological Chemistry

Bromodomain Protein 4 Mediates the Papillomavirus E2 Transcriptional Activation Function

Michal R. Schweiger, Jianxin You, Peter M. Howley

Journal of Virology

Viral ReplicationAmino AcidsMolecular BiologyChromosome TetherCancer-associated Virus +16

A HECT Domain E3 Enzyme Assembles Novel Polyubiquitin Chains

Jianxin You, Cecile M. Pickart

Journal of Biological Chemistry

Merkel Cell Polyomavirus Large T Antigen Disrupts Host Genomic Integrity and Inhibits Cellular Proliferation

Jing Li, Xin Wang, Jason Diaz, +3

Journal of Virology

ImmunologyImmunoeditingPathologyInhibits Cellular ProliferationMerkel Cell Polyomavirus +16

Recruitment of Brd4 to the Human Papillomavirus Type 16 DNA Replication Complex Is Essential for Replication of Viral DNA

Xin Wang, Christine M. Helfer, Neha J. Pancholi, +2

Journal of Virology

Viral DnaViral ReplicationViral Polymerase StructureViral Polymerase MechanismMolecular Biology +15

Bromodomain Protein Brd4 Plays a Key Role in Merkel Cell Polyomavirus DNA Replication

Xin Wang, Jing Li, Rachel M. Schowalter, +3

PLoS Pathogens

Viral ReplicationKey RoleImmunologyMolecular BiologyMolecular Genetics +16