Takashi Yoshikado

Quantitative Analyses of Hepatic OATP‐Mediated Interactions Between Statins and Inhibitors Using PBPK Modeling With a Parameter Optimization Method

Takashi Yoshikado, Kenta Yoshida, Naoki Kotani et al. · Clinical Pharmacology & Therapeutics · 2016 · 93 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Comparative Study of the Dose-Dependence of OATP1B Inhibition by Rifampicin Using Probe Drugs and Endogenous Substrates in Healthy Volunteers

Issey Takehara, Takashi Yoshikado, Keiko Ishigame et al. · Pharmaceutical Research · 2018 · 90 citations

Medicine, Pharmacokinetics, Pharmacology +8

Itraconazole-Induced Cholestasis: Involvement of the Inhibition of Bile Canalicular Phospholipid Translocator MDR3/ABCB4

Takashi Yoshikado, Tappei Takada, Takehito Yamamoto et al. · Molecular Pharmacology · 2010 · 80 citations

Medicine, Biochemistry, Pharmacology +17

PBPK Modeling of Coproporphyrin I as an Endogenous Biomarker for Drug Interactions Involving Inhibition of Hepatic OATP1B1 and OATP1B3

Takashi Yoshikado, Kota Toshimoto, Kazuya Maeda et al. · CPT Pharmacometrics & Systems Pharmacology · 2018 · 75 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Investigation of Glycochenodeoxycholate Sulfate and Chenodeoxycholate Glucuronide as Surrogate Endogenous Probes for Drug Interaction Studies of OATP1B1 and OATP1B3 in Healthy Japanese Volunteers

Issey Takehara, Hanano Terashima, Takeshi Nakayama et al. · Pharmaceutical Research · 2017 · 72 citations

Medicine, Pharmacokinetics, Pharmacology +7