Hirohisa Miyashita

Loss of System x_c⁻Does Not Induce Oxidative Stress But Decreases Extracellular Glutamate in Hippocampus and Influences Spatial Working Memory and Limbic Seizure Susceptibility

Dimitri De Bundel, Anneleen Schallier, Ellen Loyens et al. · Journal of Neuroscience · 2011 · 203 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

SCO-267, a GPR40 Full Agonist, Improves Glycemic and Body Weight Control in Rat Models of Diabetes and Obesity

Hikaru Ueno, Ryo Ito, Shinichi Abe et al. · Journal of Pharmacology and Experimental Therapeutics · 2019 · 36 citations · Full text

Medicine, Endocrinology, Pharmacology +17

Discovery of a novel series of indoline carbamate and indolinylpyrimidine derivatives as potent GPR119 agonists

Kenjiro Sato, Hiromichi Sugimoto, Kentaro Rikimaru et al. · Bioorganic & Medicinal Chemistry · 2014 · 29 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8

GPR40 full agonism exerts feeding suppression and weight loss through afferent vagal nerve

Hikaru Ueno, Ryo Ito, Shinichi Abe et al. · PLoS ONE · 2019 · 21 citations · Full text

Life Sciences, Endocrinology, Pharmacology +16

Discovery of a novel series of GPR119 agonists: Design, synthesis, and biological evaluation of N-(Piperidin-4-yl)-N-(trifluoromethyl)pyrimidin-4-amine derivatives

Osamu Kubo, Kazuaki Takami, Masahiro Kamaura et al. · Bioorganic & Medicinal Chemistry · 2021 · 20 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16