Andrew X. Zhang

A Remote Arene-Binding Site on Prostate Specific Membrane Antigen Revealed by Antibody-Recruiting Small Molecules

Andrew X. Zhang, Ryan P. Murelli, Cyril Bařinka et al. · Journal of the American Chemical Society · 2010 · 161 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +15

Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}-<i>N</i>-methylpyridine-2-carboxamide (AZD5305): A PARP1–DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPs

Jeffrey W. Johannes, Amber Balazs, Derek Barratt et al. · Journal of Medicinal Chemistry · 2021 · 140 citations · Full text

Life Sciences, Medicinal Chemistry, Oncology +13

Chemical Control over Immune Recognition: A Class of Antibody-Recruiting Small Molecules That Target Prostate Cancer

Ryan P. Murelli, Andrew X. Zhang, Julien Michel et al. · Journal of the American Chemical Society · 2009 · 130 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

CETSA beyond Soluble Targets: a Broad Application to Multipass Transmembrane Proteins

Aarti Kawatkar, Michelle Schefter, Nils-Olov Hermansson et al. · ACS Chemical Biology · 2019 · 92 citations

Life Sciences, Biochemistry, Molecular Biology +13

Chemically Synthesized Molecules with the Targeting and Effector Functions of Antibodies

Patrick J. McEnaney, Kelly Fitzgerald, Andrew X. Zhang et al. · Journal of the American Chemical Society · 2014 · 52 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +17