Jacob M. Berman

Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer

Léo Aubert, Neethi Nandagopal, Zachary Steinhart et al. · Nature Communications · 2020 · 314 citations · Full text

Medicine, Molecular Biology, Oncology +16

A noncoding single-nucleotide polymorphism at 8q24 drives <i>IDH1</i> -mutant glioma formation

Connor Yanchus, Kristen Drucker, Thomas M. Kollmeyer et al. · Science · 2022 · 69 citations · Full text

Medicine, Genetics, Molecular Genetics +17

In vivo CRISPR screens reveal Serpinb9 and Adam2 as regulators of immune therapy response in lung cancer

Dzana Dervovic, Ahmad Malik, Edward L.Y. Chen et al. · Nature Communications · 2023 · 40 citations · Full text

Medicine, Cancer Biology, Oncology +17

Simultaneous inhibition of Sirtuin 3 and cholesterol homeostasis targets acute myeloid leukemia stem cells by perturbing fatty acid β-oxidation and inducing lipotoxicity

Cristiana O’Brien, Tianyi Ling, Jacob M. Berman et al. · Haematologica · 2023 · 23 citations · Full text

Life Sciences, Biochemistry, Oncology +17

Spermidine metabolism regulates leukemia stem and progenitor cell function through KAT7 expression in patient-derived mouse models

Vincent Rondeau, Jacob M. Berman, Tianyi Ling et al. · Science Translational Medicine · 2024 · 16 citations · Full text

Life Sciences, Biochemistry, Cancer Biology +17