Leon W. A. van Berkom

Elongated Multiple Electronic Cascade and Cyclization Spacer Systems in Activatible Anticancer Prodrugs for Enhanced Drug Release

Franciscus M. H. de Groot, Walter J. Loos, Ralph Koekkoek et al. · The Journal of Organic Chemistry · 2001 · 118 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Synthesis and Biological Evaluation of 2‘-Carbamate-Linked and 2‘-Carbonate-Linked Prodrugs of Paclitaxel:  Selective Activation by the Tumor-Associated Protease Plasmin

Franciscus M. H. de Groot, Leon W. A. van Berkom, Hans W. Scheeren · Journal of Medicinal Chemistry · 2000 · 103 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Synthesis of Spirohydantoins and Spiro-2,5-diketopiperazines via Resin-Bound Cyclic α,α-Disubstituted α-Amino Esters

George J. T. Kuster, Leon W. A. van Berkom, Mohamed Kalmoua et al. · Journal of Combinatorial Chemistry · 2005 · 41 citations

Pharmacy, Chemistry, Medicinal Chemistry +15

A novel domino (4+2)/(4+2)/(3+2) cycloaddition reaction leading to highly functionalized polycyclic nitroso acetals

Leon W. A. van Berkom, George J. T. Kuster, F. Kalmoua et al. · Tetrahedron Letters · 2003 · 28 citations

Natural Sciences, Chemistry, Organic Chemistry +12

Synthesis and Rearrangement of <i>N</i>‐Organyloxy β‐Lactams Derived from a (4+2)/(3+2) Sequential Cycloaddition Reaction Involving Enol Ethers and Nitro Alkenes

Leon W. A. van Berkom, George J. T. Kuster, R. De Gelder et al. · European Journal of Organic Chemistry · 2004 · 19 citations

Pharmacy, Chemistry, Medicinal Chemistry +9