Michael DiDonato - Concepedia

Author

Michael DiDonato

Genomics Institute of the Novartis Research Foundation ORCID

Also Known As

M. DiDonato, Michael DiDonato, Mike DiDonato

Publications

Citations

H-Index

Concepts

All Affiliations

Genomics Institute of the Novartis Research Foundation Scripps Research Institute Stanford University Stanford Synchrotron Radiation Lightsource Joint Center for Structural Genomics

About

Michael DiDonato is an author at Genomics Institute of the Novartis Research Foundation specializing in natural sciences, molecular biology, and medicine.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	12	12	1.3K
2	Natural Sciences	12	14	490
3	Biochemistry	12	14	490
4	Biomolecular Engineering	3	3	100
5	Engineering	2	2	55

Michael DiDonato

Publications

2.3K

Citations

H-Index

Page 1

	Year	Citations
Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitors Yong Jia, Cai‐Hong Yun, Eunyoung Park, Nature Molecular PharmacologyMedicinePharmacologyMutant-selective Allosteric InhibitorsNovel Therapy	2016	851
Inhibition of DYRK1A and GSK3B induces human β-cell proliferation Weijun Shen, Brandon L. Taylor, Qihui Jin, Nature Communications	2015	198
Expression, Purification, and Metal Binding Properties of the N-terminal Domain from the Wilson Disease Putative Copper-transporting ATPase (ATP7B) Michael DiDonato, Suree Narindrasorasak, John Forbes, Journal of Biological Chemistry	1997	164
Superoxide Dismutase from the Eukaryotic Thermophile Alvinella pompejana: Structures, Stability, Mechanism, and Insights into Amyotrophic Lateral Sclerosis David Shin, Michael DiDonato, D.P. Barondeau, Journal of Molecular Biology Amyotrophic Lateral SclerosisCellular EnzymologyBiochemistryNatural SciencesMolecular Biology	2008	141
EGF816 Exerts Anticancer Effects in Non–Small Cell Lung Cancer by Irreversibly and Selectively Targeting Primary and Acquired Activating Mutations in the EGF Receptor Yong Jia, Jose Juarez, Jie Li, Cancer Research	2016	120
Copper-Induced Conformational Changes in the N-Terminal Domain of the Wilson Disease Copper-Transporting ATPase Michael DiDonato, Hua-Fen Hsu, Suree Narindrasorasak, Biochemistry	2000	111
Discovery of (<i>R</i>,<i>E</i>)-<i>N</i>-(7-Chloro-1-(1-[4-(dimethylamino)but-2-enoyl]azepan-3-yl)-1<i>H</i>-benzo[<i>d</i>]imidazol-2-yl)-2-methylisonicotinamide (EGF816), a Novel, Potent, and WT Sparing Covalent Inhibitor of Oncogenic (L858R, ex19del) and Resistant (T790M) EGFR Mutants for the Treatment of EGFR Mutant Non-Small-Cell Lung Cancers G. Lelais, Robert Epple, Thomas H. Marsilje, Journal of Medicinal Chemistry Tumor BiologyGood Wt-egfr SelectivityNew TherapiesEgfr MutantsAnti-cancer Agent	2016	94
Insights into Lou Gehrig's Disease from the Structure and Instability of the A4V Mutant of Human Cu,Zn Superoxide Dismutase Rosa M. F. Cardoso, M.M. Thayer, Michael DiDonato, Journal of Molecular Biology Autoimmune DiseaseBiochemistryDisease MechanismNatural SciencesPathogenesis	2002	80
Selective DYRK1A Inhibitor for the Treatment of Type 1 Diabetes: Discovery of 6-Azaindole Derivative GNF2133 Yahu A. Liu, Qihui Jin, Yefen Zou, Journal of Medicinal Chemistry	2020	74
Crystal structure of the global regulatory protein CsrA from <i>Pseudomonas putida</i> at 2.05 Å resolution reveals a new fold Chris Rife, Robert Schwarzenbacher, Daniel McMullan, Proteins Structure Function and Bioinformatics Crystal StructureNew FoldBiochemistryProtein FoldingNatural Sciences	2005	55

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