Kristine Rose

Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis

Wolfgang Hueber, Dhavalkumar D. Patel, Thaddeus P. Dryja et al. · Science Translational Medicine · 2010 · 861 citations

Medicine, Immunology, Pharmacology +17

Human ADP-ribosylation Factor-activated Phosphatidylcholine-specific Phospholipase D Defines a New and Highly Conserved Gene Family

Scott M. Hammond, Yelena M. Altshuller, Tsung-Chang Sung et al. · Journal of Biological Chemistry · 1995 · 660 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +9

A Phase I, Multicenter, Open-Label, First-in-Human, Dose-Escalation Study of the Oral Smoothened Inhibitor Sonidegib (LDE225) in Patients with Advanced Solid Tumors

Jordi Rodón, Hussein Tawbi, Anne Thomas et al. · Clinical Cancer Research · 2014 · 231 citations · Full text

Pharmacy, Oncology, Pharmacology +17

Phospholipase D signaling is essential for meiosis.

Kristine Rose, Simon A. Rudge, Michael A. Frohman et al. · Proceedings of the National Academy of Sciences · 1995 · 209 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Targeting activated PI3K/mTOR signaling overcomes acquired resistance to CDK4/6-based therapies in preclinical models of hormone receptor-positive breast cancer

Neil A. O’Brien, Martina S.J. McDermott, Dylan Conklin et al. · Breast Cancer Research · 2020 · 156 citations · Full text

Medicine, Oncology, Pharmacology +16