Martina S.J. McDermott

In vitro Development of Chemotherapy and Targeted Therapy Drug-Resistant Cancer Cell Lines: A Practical Guide with Case Studies

Martina S.J. McDermott, Alex J. Eustace, Steven Busschots et al. · Frontiers in Oncology · 2014 · 317 citations · Full text

Medicine, Oncology, Pharmacology +16

Targeting activated PI3K/mTOR signaling overcomes acquired resistance to CDK4/6-based therapies in preclinical models of hormone receptor-positive breast cancer

Neil A. O’Brien, Martina S.J. McDermott, Dylan Conklin et al. · Breast Cancer Research · 2020 · 156 citations · Full text

Medicine, Oncology, Pharmacology +16

CDK8/19 Mediator kinases potentiate induction of transcription by NFκB

Mengqian Chen, Jiaxin Liang, Hao Ji et al. · Proceedings of the National Academy of Sciences · 2017 · 140 citations

Life Sciences, Cell Biology, Oncology +17

Inhibition of CDK8 mediator kinase suppresses estrogen dependent transcription and the growth of estrogen receptor positive breast cancer

Martina S.J. McDermott, Alexander A. Chumanevich, Chang‐Uk Lim et al. · Oncotarget · 2017 · 131 citations · Full text

Medicine, Cancer Biology, Oncology +17

Concise total syntheses of (–)-jorunnamycin A and (–)-jorumycin enabled by asymmetric catalysis

Eric R. Welin, Aurapat Ngamnithiporn, Max Klatte et al. · Science · 2018 · 121 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13