Florian Wegwitz

Exosomal cellular prion protein drives fibrillization of amyloid beta and counteracts amyloid beta‐mediated neurotoxicity

Clemens Falker, A. Hartmann, Inga Guett et al. · Journal of Neurochemistry · 2015 · 156 citations · Full text

TNF-α-producing macrophages determine subtype identity and prognosis via AP1 enhancer reprogramming in pancreatic cancer

Mengyu Tu, Lukas Klein, Elisa Espinet et al. · Nature Cancer · 2021 · 110 citations

Pancreatic Cancer, Medicine, Subtype Identity +8

Histone deacetylase class-I inhibition promotes epithelial gene expression in pancreatic cancer cells in a BRD4- and MYC-dependent manner

Vivek Kumar Mishra, Florian Wegwitz, Robyn Laura Kosinsky et al. · Nucleic Acids Research · 2017 · 91 citations · Full text

Aggressive Cancer, Myc Occupancy, Pancreatic Cancer Cells +22

The histone methyltransferase DOT1L is required for proper DNA damage response, DNA repair, and modulates chemotherapy responsiveness

Vijayalakshmi Kari, Sanjay Kumar Raul, Jana Maria Henck et al. · Clinical Epigenetics · 2019 · 74 citations · Full text

Krüppel-like Transcription Factor KLF10 Suppresses TGFβ-Induced Epithelial-to-Mesenchymal Transition via a Negative Feedback Mechanism

Vivek Kumar Mishra, Malayannan Subramaniam, Vijayalakshmi Kari et al. · Cancer Research · 2017 · 71 citations · Full text