Lukas Klein

Fibroblast drug scavenging increases intratumoural gemcitabine accumulation in murine pancreas cancer

Melanie S. Patzak, Lukas Klein, N Chen et al. · Gut · 2017 · 192 citations · Full text

TNF-α-producing macrophages determine subtype identity and prognosis via AP1 enhancer reprogramming in pancreatic cancer

Mengyu Tu, Lukas Klein, Elisa Espinet et al. · Nature Cancer · 2021 · 110 citations

Pancreatic Cancer, Medicine, Subtype Identity +8

HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses

Simon Langer, Christian Hammer, Kristina Hopfensperger et al. · eLife · 2019 · 80 citations · Full text

IL-17A-producing CD8 ⁺ T cells promote PDAC via induction of inflammatory cancer-associated fibroblasts

Felix S.R. Picard, Veronika Lutz, Anna Brichkina et al. · Gut · 2023 · 72 citations · Full text

Process intensification in the biopharma industry: Improving efficiency of protein manufacturing processes from development to production scale using synergistic approaches

Dirk Müller, Lukas Klein, Johannes R. Lemke et al. · Chemical Engineering and Processing - Process Intensification · 2021 · 68 citations · Full text

Biopharma Industry, Process Intensification, Biomanufacturing +14