John G. Woodland

First fully-automated AI/ML virtual screening cascade implemented at a drug discovery centre in Africa

Gemma Turón, Jason Hlozek, John G. Woodland et al. · Nature Communications · 2023 · 75 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Chemical Proteomics and Super-resolution Imaging Reveal That Chloroquine Interacts with <i>Plasmodium falciparum</i> Multidrug Resistance-Associated Protein and Lipids

John G. Woodland, Roger Hunter, Peter J. Smith et al. · ACS Chemical Biology · 2018 · 38 citations

Medicine, Molecular Biology, Pharmacology +17

Medroxyprogesterone acetate, unlike norethisterone, increases HIV-1 replication in human peripheral blood mononuclear cells and an indicator cell line, via mechanisms involving the glucocorticoid receptor, increased CD4/CD8 ratios and CCR5 levels

Michelle F. Maritz, Roslyn M. Ray, Alexis J. Bick et al. · PLoS ONE · 2018 · 33 citations · Full text

Medicine, Endocrinology, Immunology +11

Shining new light on ancient drugs: preparation and subcellular localisation of novel fluorescent analogues of Cinchona alkaloids in intraerythrocytic Plasmodium falciparum

John G. Woodland, Roger Hunter, Peter J. Smith et al. · Organic & Biomolecular Chemistry · 2016 · 27 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Identification and Profiling of a Novel Diazaspiro[3.4]octane Chemical Series Active against Multiple Stages of the Human Malaria Parasite <i>Plasmodium falciparum</i> and Optimization Efforts

Claire Le Manach, Jean Dam, John G. Woodland et al. · Journal of Medicinal Chemistry · 2021 · 23 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16