Central Role of Defective Interleukin-2 Production in the Triggering of Islet Autoimmune Destruction

Qizhi Tang, Jason Y. Adams, Cristina Peñaranda, +6

Immunity

InflammationCytokineCentral RoleIslet Autoimmune DestructionDefective Interleukin-2 Production +11

Tissue-resident FOLR2+ macrophages associate with CD8+ T cell infiltration in human breast cancer

Rodrigo Nalio Ramos, Yoann Missolo-Koussou, Yohan Gerber-Ferder, +31

Cell

Cancer ImmunosurveillanceImmunologyTumor ImmunityHuman Breast CancerImmunologic Mechanism +6

IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells

Yenkel Grinberg‐Bleyer, Audrey Baeyens, Sylvaine You, +11

The Journal of Experimental Medicine

CD39 Expression Defines Cell Exhaustion in Tumor-Infiltrating CD8+ T Cells

Fernando P. Canale, María C. Ramello, Nicolás Gonzalo Núñez, +11

Cancer Research

Regulatory T cells delay disease progression in Alzheimer-like pathology

Cira Dansokho, Dylla Ait Ahmed, Saba Aïd, +8

Brain

Transcriptional and Functional Analysis of CD1c+ Human Dendritic Cells Identifies a CD163+ Subset Priming CD8+CD103+ T Cells

Pierre Bourdely, Giorgio Anselmi, Kristīne Vaivode, +13

Immunity

Peptide–TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T-cell immunity to tumor antigens

Geoffrey M. Lynn, Christine Sedlik, Faezzah Baharom, +27

Nature Biotechnology

VaccinationNanomedicineCross-protectionTumor ImmunologyImmunology +10

Tumor invasion in draining lymph nodes is associated with Treg accumulation in breast cancer patients

Nicolás Gonzalo Núñez, Jimena Tosello, Rodrigo Nalio Ramos, +18

Nature Communications

Clonally Expanded T Cells Reveal Immunogenicity of Rhabdoid Tumors

Amaury Leruste, Jimena Tosello, Rodrigo Nalio Ramos, +28

Cancer Cell

Cancer ImmunosurveillanceRhabdoid TumorsImmunologyTumor ImmunityImmunotherapy +2

Pathogenic T cells have a paradoxical protective effect in murine autoimmune diabetes by boosting Tregs

Yenkel Grinberg‐Bleyer, David Saadoun, Audrey Baeyens, +11

Journal of Clinical Investigation

Paradoxical Protective EffectT-regulatory CellImmunologyRegulatory T CellsImmunotherapy +16