Michael A. Collingwood

Identification of preexisting adaptive immunity to Cas9 proteins in humans

Carsten T. Charlesworth, Priyanka S. Deshpande, Daniel P. Dever et al. · Nature Medicine · 2019 · 975 citations · Full text

Life Sciences, Genetics, Molecular Biology +9

A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells

Christopher A. Vakulskas, Daniel P. Dever, Garrett R. Rettig et al. · Nature Medicine · 2018 · 801 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease

Kiran Musunuru, Sarah Grandinette, Xiao Wang et al. · New England Journal of Medicine · 2025 · 278 citations · Full text

Life Sciences, Biotechnology, Molecular Genetics +17

AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines

Liyang Zhang, John A. Zuris, Ramya Viswanathan et al. · Nature Communications · 2021 · 172 citations · Full text

Life Sciences, Biotechnology, Oncology +15

Simplified CRISPR tools for efficient genome editing and streamlined protocols for their delivery into mammalian cells and mouse zygotes

Ashley M. Jacobi, Garrett R. Rettig, Rolf Turk et al. · Methods · 2017 · 158 citations · Full text

Life Sciences, Genetics, Molecular Biology +15