Christopher A. Vakulskas

Identification of preexisting adaptive immunity to Cas9 proteins in humans

Carsten T. Charlesworth, Priyanka S. Deshpande, Daniel P. Dever et al. · Nature Medicine · 2019 · 924 citations · Full text

Immunological Memory, Immunogenetics, Cas9 Proteins +10

A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells

Christopher A. Vakulskas, Daniel P. Dever, Garrett R. Rettig et al. · Nature Medicine · 2018 · 771 citations · Full text

Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases

Matthew T. N. Yarnall, Eleonora Ioannidi, Cian Schmitt-Ulms et al. · Nature Biotechnology · 2022 · 395 citations · Full text

Drag-and-drop Genome Insertion, Genetics, Genetic Engineering +11

Global role of the bacterial post-transcriptional regulator CsrA revealed by integrated transcriptomics

Anastasia H. Potts, Christopher A. Vakulskas, Archana Pannuri et al. · Nature Communications · 2017 · 181 citations · Full text

Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease

Kiran Musunuru, Sarah Grandinette, Xiao Wang et al. · New England Journal of Medicine · 2025 · 179 citations · Full text

Genetic Diseases, Genome Surgery, In Vivo Gene Therapy +15