Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells

Harveer Dev, Ting-Wei Chiang, Chloé Lescale, +26

Nature Cell Biology

ChromatinGenome InstabilityMedicineMolecular BiologyShieldin Complex Promotes +5

ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks

Gabriel Balmus, Domenic Pilger, Julia Coates, +20

Nature Communications

Genome architecture and stability in the Saccharomyces cerevisiae knockout collection

Fabio Puddu, Mareike Herzog, Alexandra Selivanova, +12

Nature

Sequence AssemblyNatural SciencesGeneticsGenome StructureDna Replication +6

Trajectory and uniqueness of mutational signatures in yeast mutators

Sophie Loeillet, Mareike Herzog, Fabio Puddu, +4

Proceedings of the National Academy of Sciences

Synthetic viability genomic screening defines Sae2 function in DNA repair

Fabio Puddu, Tobias Oelschlaegel, Ilaria Guerini, +10

The EMBO Journal

Global reorganization of budding yeast chromosome conformation in different physiological conditions

Elisa Dultz, Harianto Tjong, Elodie Weider, +7

The Journal of Cell Biology

GeneticsGenomic MechanismMolecular BiologyMolecular GeneticsEpigenetics +17

Genome-wide genetic screening with chemically mutagenized haploid embryonic stem cells

Josep V. Forment, Mareike Herzog, Julia Coates, +6

Nature Chemical Biology

Developmental BiologyGenome-wide Genetic ScreeningMedicineGeneticsStem Cell Research +4

Chronic irradiation of human cells reduces histone levels and deregulates gene expression

Donna Lowe, Mareike Herzog, Thorsten Mosler, +6

Scientific Reports

Mutagenic mechanisms of cancer-associated DNA polymerase ϵ alleles

Mareike Herzog, Elisa Alonso‐Perez, Israel Salguero, +4

Nucleic Acids Research

ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks

Gabriel Balmus, Domenic Pilger, Julia Coates, +20