A nanoparticle-incorporated STING activator enhances antitumor immunity in PD-L1–insensitive models of triple-negative breast cancer

Ning Cheng, Rebekah Watkins-Schulz, Robert D. Junkins, +13

JCI Insight

A noncanonical function of cGAMP in inflammasome priming and activation

Karen V. Swanson, Robert D. Junkins, Cathryn J. Kurkjian, +7

The Journal of Experimental Medicine

A robust microparticle platform for a STING-targeted adjuvant that enhances both humoral and cellular immunity during vaccination

Robert D. Junkins, Matthew D. Gallovic, Brandon M. Johnson, +11

Journal of Controlled Release

VaccinationMucosal VaccinationCross-protectionVaccine DevelopmentVaccine Target +10

Autophagy Enhances Bacterial Clearance during P. aeruginosa Lung Infection

Robert D. Junkins, Ann Shen, Kirill V. Rosen, +2

PLoS ONE

InflammationCell AutophagyLung InflammationMedicineVirulence Factor +13

A microparticle platform for STING-targeted immunotherapy enhances natural killer cell- and CD8+ T cell-mediated anti-tumor immunity

Rebekah Watkins-Schulz, Pamela Tiet, Matthew D. Gallovic, +5

Biomaterials

Tumor ImmunologySting-targeted ImmunotherapyCancer ImmunosurveillanceImmunologyTumor Immunity +8

Acetalated Dextran Microparticles for Codelivery of STING and TLR7/8 Agonists

Michael A. Collier, Robert D. Junkins, Matthew D. Gallovic, +7

Molecular Pharmaceutics

Pharmaceutical ScienceInnate Immune SystemImmunologyImmunotherapeuticsInnate Immunity +19

IFN Regulatory Factor 3 Contributes to the Host Response during <i>Pseudomonas aeruginosa</i> Lung Infection in Mice

Svetlana O. Carrigan, Robert D. Junkins, Yong Yang, +4

The Journal of Immunology

Inflammatory Lung DiseaseMicrobial PathogensLung InflammationInnate Immune SystemImmunology +21

Regulator of Calcineurin 1 Suppresses Inflammation during Respiratory Tract Infections

Robert D. Junkins, Adam J. MacNeil, Zhengli Wu, +2

The Journal of Immunology

Acute Lung InjuryInflammatory Lung DiseaseMicrobial PathogensLung InflammationInnate Immune System +19

The AAA-ATPase p97 facilitates degradation of apolipoprotein B by the ubiquitin-proteasome pathway

Eric A. Fisher, Louis R. Lapierre, Robert D. Junkins, +1

Journal of Lipid Research

Regulator of calcineurin 1 differentially regulates TLR-dependent MyD88 and TRIF signaling pathways

Zheng Pang, Robert D. Junkins, Renee Raudonis, +4

PLoS ONE

Inflammatory Lung DiseaseMicrobial PathogensMolecular RegulationInnate Immune SystemImmunology +31