James C. Mulloy

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

Johannes Zuber, Junwei Shi, Eric Wang et al. · Nature · 2011 · 1.9K citations

Hematological Malignancy, Hematology, Myeloid Neoplasia +7

R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling

Rui Su, Lei Dong, Chenying Li et al. · Cell · 2017 · 1.2K citations · Full text

Tumor Biology, Medicine, Tumor Suppressor +3

METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification

Hengyou Weng, Huilin Huang, Huizhe Wu et al. · Cell stem cell · 2017 · 993 citations · Full text

Hematological Malignancy, Medicine, Mixed-phenotype Acute Leukemia +9

Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia

Yue Huang, Rui Su, Yue Sheng et al. · Cancer Cell · 2019 · 825 citations · Full text

Hematological Malignancy, Biochemistry, Natural Sciences +8

Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion

Rui Su, Lei Dong, Yangchan Li et al. · Cancer Cell · 2020 · 742 citations · Full text

Immune Evasion, Medicine, Stem Cell Mobilization +8