Compounds Triggering ER Stress Exert Anti-Melanoma Effects and Overcome BRAF Inhibitor Resistance

Michaël Cerezo, Abdelali Lehraiki, Antoine Millet, +27

Cancer Cell

MedicinePhotocarcinogenesisMelanomaAnti-cancer AgentDermatology +4

Metformin Blocks Melanoma Invasion and Metastasis Development in AMPK/p53-Dependent Manner

Michaël Cerezo, Mélanie Tichet, Patricia Abbe, +10

Molecular Cancer Therapeutics

Ampk/p53-dependent MannerTumor BiologyOncologyMedicineMetformin Inhibits +12

Inhibition of Melanogenesis by the Antidiabetic Metformin

Abdelali Lehraiki, Patricia Abbe, Michaël Cerezo, +7

Journal of Investigative Dermatology

MedicineInsulin ManagementDiabetesGlycobiologyAntidiabetic Metformin +4

Increased CD271 expression by the NF-kB pathway promotes melanoma cell survival and drives acquired resistance to BRAF inhibitor vemurafenib

Abdelali Lehraiki, Michaël Cerezo, Florian Rouaud, +9

Cell Discovery

A Dock-and-Lock Mechanism Clusters ADAM10 at Cell-Cell Junctions to Promote α-Toxin Cytotoxicity

Jimit Shah, Florian Rouaud, Diego Guerrera, +7

Cell Reports

α-Toxin CytotoxicitySignal TransductionCell InteractionMolecular BiologyCell-matrix Interaction +7

E2F1 inhibition mediates cell death of metastatic melanoma

Florian Rouaud, Nedra Hamouda‐Tekaya, Michaël Cerezo, +15

Cell Death and Disease

Rapid decay of engulfed extracellular miRNA by XRN1 exonuclease promotes transient epithelial-mesenchymal transition

Joséphine Zangari, Marius Ilié, Florian Rouaud, +12

Nucleic Acids Research

EngineeringExtracellular MicrovesiclesCancer BiologyEngulfed MirnaTumor Biology +19

Cingulin binds to the ZU5 domain of scaffolding protein ZO-1 to promote its extended conformation, stabilization, and tight junction accumulation

Ekaterina Vasileva, Domenica Spadaro, Florian Rouaud, +8

Journal of Biological Chemistry

Uncovering and deciphering the pro-invasive role of HACE1 in melanoma cells

Najla El Hachem, Nadia Habel, Tanesha Naiken, +11

Cell Death and Differentiation

Cell RegulationMedicineMelanomaMelanoma CellsPro-invasive Role +6

Cingulin and paracingulin tether myosins-2 to junctions to mechanoregulate the plasma membrane

Florian Rouaud, Wenmao Huang, Arielle Flinois, +12

The Journal of Cell Biology

Spatial SortingMolecular BiologyCytoskeletonCellular PhysiologyNeuromuscular Junction +21