EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy

Joachim Lupberger, Mirjam B. Zeisel, Fei Xiao, +23

Nature Medicine

Viral HepatitisHost FactorsImmunologyAntiviral TherapyHepatitis +4

Rapid induction of virus-neutralizing antibodies and viral clearance in a single-source outbreak of hepatitis C

Jan M. Pestka, Mirjam B. Zeisel, Edith Bläser, +11

Proceedings of the National Academy of Sciences

VaccinationAcute Hepatitis CViral PersistenceRapid InductionHepatitis C +13

HCV-Induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response

Nourdine Hamdane, Frank Jühling, Émilie Crouchet, +32

Gastroenterology

Scavenger receptor class B type I is a key host factor for hepatitis C virus infection required for an entry step closely linked to CD81

Mirjam B. Zeisel, George Koutsoudakis, Eva K. Schnober, +15

Hepatology

Apolipoprotein E Interacts With Hepatitis C Virus Nonstructural Protein 5A and Determines Assembly of Infectious Particles

Wagané Joseph Antoine Benga, Sophie Krieger, Maria Dimitrova, +8

Hepatology

Hepatitis C Virus Hypervariable Region 1 Modulates Receptor Interactions, Conceals the CD81 Binding Site, and Protects Conserved Neutralizing Epitopes

Dorothea Bankwitz, Eike Steinmann, Julia Bitzegeio, +9

Journal of Virology

Viral ReplicationRna ReplicationImmunologyMolecular BiologyLow Density +14

Inhibition of hepatitis C virus infection by anti‐claudin‐1 antibodies is mediated by neutralization of E2–CD81–Claudin‐1 associations†

Sophie Krieger, Mirjam B. Zeisel, Christopher Davis, +14

Hepatology

HRas Signal Transduction Promotes Hepatitis C Virus Cell Entry by Triggering Assembly of the Host Tetraspanin Receptor Complex

Laetitia Zona, Joachim Lupberger, Nazha Sidahmed‐Adrar, +18

Cell Host & Microbe

Viral ReplicationSignal TransductionViral HepatitisImmunologyHepatitis +6

A targeted functional RNA interference screen uncovers glypican 5 as an entry factor for hepatitis B and D viruses

Éloi R. Verrier, Che C. Colpitts, C Bach, +18

Hepatology

Geraniol, a component of plant essential oils, modulates DNA synthesis and potentiates 5-fluorouracil efficacy on human colon tumor xenografts

Stéphanie Carnésecchi, Rui Bras-Gonçalves, Amyaouch Bradaïa, +4

Cancer Letters

Tumor BiologyPolyphenolics5-Fluorouracil EfficacyMedicinePlant Essential Oils +7