Karl J. M. Hanf

Affinity enhancement of an in vivo matured therapeutic antibody using structure‐based computational design

Louis A. Clark, P. Ann Boriack‐Sjodin, John Eldredge et al. · Protein Science · 2006 · 180 citations · Full text

Crystal Structure, Engineering, Protein Assembly +24

Structural understanding of stabilization patterns in engineered bispecific Ig‐like antibody molecules

Jacob L. Jordan, Joseph W. Arndt, Karl J. M. Hanf et al. · Proteins Structure Function and Bioinformatics · 2009 · 38 citations

Antibody humanization by redesign of complementarity-determining region residues proximate to the acceptor framework

Karl J. M. Hanf, Joseph W. Arndt, Ling Ling Chen et al. · Methods · 2013 · 25 citations

Immunocytochemical Technique, Antibody Humanization, Natural Sciences +12

Functional activity of anti-LINGO-1 antibody opicinumab requires target engagement at a secondary binding site

Karl J. M. Hanf, Joseph W. Arndt, Yuting Liu et al. · mAbs · 2020 · 21 citations · Full text

Immunology, Immunotherapy, Anti-lingo-1 Antibody +22