Small-Molecule Inhibition of TNF-α

Molly M. He, Annemarie Stroustrup, Johan D. Oslob, +17

Science

ImmunologyCell DeathMolecular BiologyInflammationTnf-alpha Subunits +15

Affinity enhancement of an in vivo matured therapeutic antibody using structure‐based computational design

Louis A. Clark, P. Ann Boriack‐Sjodin, John Eldredge, +12

Protein Science

Crystal StructureEngineeringProtein AssemblyBiomolecular Structure PredictionHydrogen Bond Network +22

A novel platform for engineering blood‐brain barrier‐crossing bispecific biologics

Graham K. Farrington, Nadia L. Caram‐Salas, Arsalan S. Haqqani, +12

The FASEB Journal

Improving the solubility of anti‐LINGO‐1 monoclonal antibody Li33 by isotype switching and targeted mutagenesis

R. Blake Pepinsky, Laura Silvian, Steven A. Berkowitz, +8

Protein Science

Endosomal trafficking regulates receptor-mediated transcytosis of antibodies across the blood brain barrier

Arsalan S. Haqqani, Christie E. Delaney, Eric Brunette, +7

Journal of Cerebral Blood Flow & Metabolism

Immunocytochemical TechniqueImmunologyCell DeathImmunotherapyNeuroinflammation +22

Formation of Virus-like Clusters Is an Intrinsic Property of the Tumor Necrosis Factor Family Member BAFF (B Cell Activating Factor)

Teresa G. Cachero, Ian M. Schwartz, Fang Qian, +12

Biochemistry

Viral PathogenesisImmunologyPathologyMolecular BiologyB Cell Development +15

Nucleic acid hybridization assays employing dA-tailed capture probes

Massimo Lombardo, John Eldredge, Kevin R. Kearney, +2

Analytical Biochemistry

Da-tailed Capture ProbesHybridizationGeneticsBioanalysisDna Analysis +4

Immunological capture of nucleic acid hybrids and application to nonradioactive DNA probe assay.

Ayoub Rashtchian, John Eldredge, Margaret Ottaviani, +5

Clinical Chemistry

Pathogen DetectionPolystyrene Test TubesImmunologyDna AnalysisMolecular Biology +21

Stoichiometry of LTβR Binding to LIGHT

John Eldredge, Steven A. Berkowitz, Alan F. Corin, +7

Biochemistry

Signal TransductionHomotypic TrimerBiochemistryPhotochemistryTrimeric Ligand +12

An antibody loop replacement design feasibility study and a loop-swapped dimer structure

Lewis A. Clark, P. Ann Boriack‐Sjodin, Eric S. Day, +7

Protein Engineering Design and Selection