John Eldredge

Small-Molecule Inhibition of TNF-α

Molly M. He, Annemarie Stroustrup, Johan D. Oslob et al. · Science · 2005 · 565 citations

Immunology, Cell Death, Molecular Biology +17

Affinity enhancement of an in vivo matured therapeutic antibody using structure‐based computational design

Louis A. Clark, P. Ann Boriack‐Sjodin, John Eldredge et al. · Protein Science · 2006 · 180 citations · Full text

Crystal Structure, Engineering, Protein Assembly +24

A novel platform for engineering blood‐brain barrier‐crossing bispecific biologics

Graham K. Farrington, Nadia L. Caram‐Salas, Arsalan S. Haqqani et al. · The FASEB Journal · 2014 · 145 citations · Full text

Improving the solubility of anti‐LINGO‐1 monoclonal antibody Li33 by isotype switching and targeted mutagenesis

R. Blake Pepinsky, Laura Silvian, Steven A. Berkowitz et al. · Protein Science · 2010 · 101 citations · Full text

Endosomal trafficking regulates receptor-mediated transcytosis of antibodies across the blood brain barrier

Arsalan S. Haqqani, Christie E. Delaney, Eric Brunette et al. · Journal of Cerebral Blood Flow & Metabolism · 2017 · 99 citations · Full text

Immunocytochemical Technique, Immunology, Cell Death +24