An early decrease in Notch activation is required for human TCR-αβ lineage differentiation at the expense of TCR-γδ T cells

Inge Van de Walle, Greet De Smet, Magda De Smedt, +4

Blood

Specific Notch receptor–ligand interactions control human TCR-αβ/γδ development by inducing differential Notch signal strength

Inge Van de Walle, Els Waegemans, Jelle De Medts, +12

The Journal of Experimental Medicine

Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions

Inge Van de Walle, Greet De Smet, Martina Gärtner, +10

Blood

Notch signaling is required for proliferation but not for differentiation at a well-defined β-selection checkpoint during human T-cell development

Tom Taghon, Inge Van de Walle, Greet De Smet, +4

Blood

Both CD34+38+ and CD34+38− Cells Home Specifically to the Bone Marrow of NOD/LtSZ <i>scid/scid</i> Mice but Show Different Kinetics in Expansion

Tessa Kerre, Greet De Smet, Magda De Smedt, +4

The Journal of Immunology

Adapted NOD/SCID model supports development of phenotypically and functionally mature T cells from human umbilical cord blood CD34+ cells

Tessa Kerre, Greet De Smet, Magda De Smedt, +7

Blood

Notch signaling induces cytoplasmic CD3ϵ expression in human differentiating NK cells

Magda De Smedt, Tom Taghon, Inge Van de Walle, +3

Blood

Overexpression of HES-1 is not sufficient to impose T-cell differentiation on human hematopoietic stem cells

Inge Hoebeke, Magda De Smedt, Inge Van de Walle, +4

Blood

CX3CL1 release during immunogenic apoptosis is associated with enhanced anti-tumour immunity

Faye Naessens, Robin Demuynck, Olga Vershinina, +8

Frontiers in Immunology