Ryan L. Powles

A Powerful Approach to Estimating Annotation-Stratified Genetic Covariance via GWAS Summary Statistics

Qiongshi Lu, Boyang Li, Derek Ou et al. · The American Journal of Human Genetics · 2017 · 225 citations · Full text

Genome-wide Association Study, Genetic Analysis, Haplotype Determination +13

CD36-Mediated Metabolic Rewiring of Breast Cancer Cells Promotes Resistance to HER2-Targeted Therapies

William W. Feng, Owen M. Wilkins, Scott Bang et al. · Cell Reports · 2019 · 199 citations · Full text

Breast Oncology, Metabolic Remodeling, Cancer Biology +19

Leveraging functional annotations in genetic risk prediction for human complex diseases

Yiming Hu, Qiongshi Lu, Ryan L. Powles et al. · PLoS Computational Biology · 2017 · 190 citations · Full text

Genetics, Polygenic Risk, Genetic Epidemiology +21

Systematic tissue-specific functional annotation of the human genome highlights immune-related DNA elements for late-onset Alzheimer’s disease

Qiongshi Lu, Ryan L. Powles, Sarah B. Abdallah et al. · PLoS Genetics · 2017 · 115 citations · Full text

Genetics, Immunology, Heritability Enrichment +22

Integrative Tissue-Specific Functional Annotations in the Human Genome Provide Novel Insights on Many Complex Traits and Improve Signal Prioritization in Genome Wide Association Studies

Qiongshi Lu, Ryan L. Powles, Qian Wang et al. · PLoS Genetics · 2016 · 103 citations · Full text

Genetics, Genomics, Gene Expression Profiling +21