Selahattin Can Özcan

6-Phosphofructo-2-kinase (PFKFB3) promotes cell cycle progression and suppresses apoptosis via Cdk1-mediated phosphorylation of p27

Brian F. Clem, Yoannis Imbert-Fernandez, Selahattin Can Özcan et al. · Cell Death and Disease · 2014 · 201 citations · Full text

Apoptosis, Cell Death, Cell Cycle +22

6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase-3 is required for transforming growth factor β1-enhanced invasion of Panc1 cells in vitro

Abdullah Yalçın, Tugba H. Solakoglu, Selahattin Can Özcan et al. · Biochemical and Biophysical Research Communications · 2017 · 42 citations

Signal Transduction, Signaling Pathway, Cell Regulation +11

PFKFB2 regulates glycolysis and proliferation in pancreatic cancer cells

Selahattin Can Özcan, Tugba H. Altunok, Ahmet Akkoç et al. · Molecular and Cellular Biochemistry · 2020 · 42 citations

Cancer Research, Signaling Pathway, Pancreatic Cancer +7

Simultaneous inhibition of PFKFB3 and GLS1 selectively kills KRAS-transformed pancreatic cells

Selahattin Can Özcan, Aydan Mutlu, Tugba H. Altunok et al. · Biochemical and Biophysical Research Communications · 2021 · 13 citations

Signal Transduction, Simultaneous Inhibition, Signaling Pathway +9