Intestinal anaerobic bacteria hydrolyse sorivudine, producing the high blood concentration of 5-(E)-(2-bromovinyl)uracil that increases the level and toxicity of 5-fluorouracil

Haruyuki Nakayama, Takemi Kinouchi, Keiko Kataoka, +3

Pharmacogenetics

High Blood ConcentrationImmunologyAntibiotic ResistanceToxicological MechanismDrug Resistance +16

Gastric acid reduction leads to an alteration in lower intestinal microflora

Takayuki Kanno, Takahiro Matsuki, Masashi Oka, +14

Biochemical and Biophysical Research Communications

NutritionDysbiosisMedicinePhysiologyGut Microbiology +11

Complete Sequencing and Diversity Analysis of the Enterotoxin-Encoding Plasmids in<i>Clostridium perfringens</i>Type A Non-Food-Borne Human Gastrointestinal Disease Isolates

Kazuaki Miyamoto, Derek J. Fisher, Jihong Li, +3

Journal of Bacteriology

Enterotoxin GeneCpe PlasmidsMicrobial PathogensPathologyComplete Sequencing +18

Genetic Characterization of Type A Enterotoxigenic Clostridium perfringens Strains

Agi Deguchi, Kazuaki Miyamoto, Tomomi Kuwahara, +5

PLoS ONE

Microbial ToxinType AGeneticsPathogenesisBacteriology +11

Prevalence and Characterization of Enterotoxin Gene-Carrying<i>Clostridium perfringens</i>Isolates from Retail Meat Products in Japan

Yasuhiro Miki, Kazuaki Miyamoto, Ikuko Kaneko-Hirano, +2

Applied and Environmental Microbiology

Mutagenicity and antimutagenicity of extracts of three spices and a medicinal plant in Thailand

Minoru Higashimoto, Juntipa Purintrapiban, Keiko Kataoka, +5

Mutation Research Letters

AllergyMedicineHerbal MedicineHerb-drug InteractionPhytopharmacology +6

Essential Involvement of CX3CR1-Mediated Signals in the Bactericidal Host Defense during Septic Peritonitis

Yuko Ishida, Takahito Hayashi, Takatsugu Goto, +4

The Journal of Immunology

Identification of Novel Clostridium perfringens Type E Strains That Carry an Iota Toxin Plasmid with a Functional Enterotoxin Gene

Kazuaki Miyamoto, Natsuko Yumine, Kanako Mimura, +4

PLoS ONE

Microbial PathogensPathogen DetectionFood Processing FacilitiesBacterial PathogensMedical Microbiology +22

Culture Supernatants of<i>Lactobacillus acidophilus</i>and<i>Bifidobacterium adolescentis</i>Repress Ileal Ulcer Formation in Rats Treated with a Nonsteroidal Antiinflammatory Drug by Suppressing Unbalanced Growth of Aerobic Bacteria and Lipid Peroxidation

Takemi Kinouchi, Keiko Kataoka, Shan Bing, +7

Microbiology and Immunology

Detection of Enterotoxigenic Clostridium perfringens in Meat Samples by Using Molecular Methods

Ikuko Kaneko, Kazuaki Miyamoto, Kanako Mimura, +4

Applied and Environmental Microbiology

Enterotoxin GeneMolecular MethodsPathogen DetectionFood Processing FacilitiesOrdinary Pcr +20