Spatial multi-omic map of human myocardial infarction

Christoph Kuppe, Ricardo O. Ramirez Flores, Zhijian Li, +39

Nature

CartographyCardiovascular DiseaseBiostatisticsHuman Myocardial InfarctionPublic Health +3

A SPAK Isoform Switch Modulates Renal Salt Transport and Blood Pressure

James A. McCormick, Kerim Mutig, Joshua H. Nelson, +8

Cell Metabolism

HypertensionUrologyRenal FunctionSodium HomeostasisMedicine +7

Skin Sodium Concentration Correlates with Left Ventricular Hypertrophy in CKD

Markus P. Schneider, Ulrike Raff, Christoph Kopp, +15

Journal of the American Society of Nephrology

Activation of the Bumetanide-sensitive Na+,K+,2Cl− Cotransporter (NKCC2) Is Facilitated by Tamm-Horsfall Protein in a Chloride-sensitive Manner

Kerim Mutig, Thomas Kahl, Turgay Saritas, +12

Journal of Biological Chemistry

ImmunologyMolecular BiologyTamm-horsfall ProteinNkcc2 ActivityCellular Physiology +19

Tamm-Horsfall Glycoprotein Interacts with Renal Outer Medullary Potassium Channel ROMK2 and Regulates Its Function

Aparna Renigunta, Vijay Renigunta, Turgay Saritas, +3

Journal of Biological Chemistry

Romk Current AmplitudesRenal PathologyCytoskeletonCellular PhysiologyRenal Function +17

mTOR-mediated podocyte hypertrophy regulates glomerular integrity in mice and humans

Victor G. Puelles, James W. van der Wolde, Nicola Wanner, +30

JCI Insight

Glomerular DiseaseRenal PathologyImmunologyCellular PhysiologyGlomerulonephritis +17

SPAK Differentially Mediates Vasopressin Effects on Sodium Cotransporters

Turgay Saritas, Aljona Borschewski, James A. McCormick, +12

Journal of the American Society of Nephrology

Short-term stimulation of the thiazide-sensitive Na⁺-Cl⁻cotransporter by vasopressin involves phosphorylation and membrane translocation

Kerim Mutig, Turgay Saritas, Shusaku Uchida, +7

American Journal of Physiology-Renal Physiology

Frequent LPA KIV-2 Variants Lower Lipoprotein(a) Concentrations and Protect Against Coronary Artery Disease

Johanna F. Schachtl‐Riess, Azin Kheirkhah, Rebecca Grüneis, +58

Journal of the American College of Cardiology

Mitochondrial DNA copy number is associated with mortality and infections in a large cohort of patients with chronic kidney disease

Federica Fazzini, Claudia Lamina, Liane Fendt, +65

Kidney International