Transient Receptor Potential Ankyrin 1 Channel Localized to Non-Neuronal Airway Cells Promotes Non-Neurogenic Inflammation

Romina Nassini, Pamela Pedretti, Nadia Moretto, +13

PLoS ONE

Unbalanced oxidant-induced DNA damage and repair in COPD: a link towards lung cancer

Gaetano Caramori, Ian M. Adcock, Paolo Casolari, +9

Thorax

Acetaminophen,<i>via</i>its reactive metabolite<i>N</i>-acetyl-<i>p</i>-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents

Romina Nassini, Serena Materazzi, Eunice Andrè, +18

The FASEB Journal

AsthmaInflammatory Lung DiseaseLung InflammationImmunologyTrpa1-deficient Mice +15

CHF6001 I: A Novel Highly Potent and Selective Phosphodiesterase 4 Inhibitor with Robust Anti-Inflammatory Activity and Suitable for Topical Pulmonary Administration

Nadia Moretto, Paola Caruso, Raffaella Bosco, +18

Journal of Pharmacology and Experimental Therapeutics

Cysteinyl‐leukotriene receptor activation in brain inflammatory reactions and cerebral edema formation: a role for transcellular biosynthesis of cysteinyl leukotrienes

Antonio Di Gennaro, Chiara Carnini, Carola Buccellati, +11

The FASEB Journal

ImmunologyBrain Permeability AlterationTranscellular BiosynthesisOxidative StressNeuroinflammation +21

Lipid Peroxidation and 5-Lipoxygenase Activity in Chronic Obstructive Pulmonary Disease

Pierachille Santus, Alessandra Sola, Paolo Carlucci, +6

American Journal of Respiratory and Critical Care Medicine

InflammationAsthmaAllergyMedicineLipid Peroxidation +6

Azithromycin inhibits nuclear factor‐<i>κ</i>B activation during lung inflammation: an in vivo imaging study

Fabio Stellari, Angelo Sala, Gaetano Donofrío, +8

Pharmacology Research & Perspectives

CHF6001 II: A Novel Phosphodiesterase 4 Inhibitor, Suitable for Topical Pulmonary Administration—In Vivo Preclinical Pharmacology Profile Defines a Potent Anti-Inflammatory Compound with a Wide Therapeutic Window

Gino Villetti, Chiara Carnini, Loredana Battipaglia, +19

Journal of Pharmacology and Experimental Therapeutics

Novel Class of Benzoic Acid Ester Derivatives as Potent PDE4 Inhibitors for Inhaled Administration in the Treatment of Respiratory Diseases

Elisabetta Armani, Gabriele Amari, Andrea Rizzi, +23

Journal of Medicinal Chemistry

AsthmaPharmaceutical ScienceInflammatory Lung DiseaseLung InflammationPotent Pde4 Inhibitors +17

Receptor for Advanced Glycation End Products Contributes to Postnatal Pulmonary Development and Adult Lung Maintenance Program in Mice

Silvia Fineschi, Giovanna De Cunto, Fabrizio Facchinetti, +10

American Journal of Respiratory Cell and Molecular Biology

AsthmaAcute Lung InjuryInflammatory Lung DiseaseLung InflammationImmunology +23