Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity

Miranda L. Broz, Mikhail Binnewies, Bijan Boldajipour, +12

Cancer Cell

Cancer ImmunosurveillanceAutoimmune DiseaseT-regulatory CellImmunologyTumor Immunity +9

Critical Role for CD103+/CD141+ Dendritic Cells Bearing CCR7 for Tumor Antigen Trafficking and Priming of T Cell Immunity in Melanoma

Edward W. Roberts, Miranda L. Broz, Mikhail Binnewies, +7

Cancer Cell

Tumor ImmunologyCancer ImmunosurveillanceCritical RoleImmunologyTumor Immunity +6

A natural killer–dendritic cell axis defines checkpoint therapy–responsive tumor microenvironments

Kevin C. Barry, Joy Hsu, Miranda L. Broz, +19

Nature Medicine

Tumor BiologyNatural Killer–dendritic CellTumor ImmunologyCancer ImmunosurveillanceMedicine +12

Unleashing Type-2 Dendritic Cells to Drive Protective Antitumor CD4+ T Cell Immunity

Mikhail Binnewies, Adriana M. Mujal, Joshua L. Pollack, +15

Cell

Cancer ImmunosurveillanceType-2 Dendritic CellsAutoimmune DiseaseImmunologyTumor Immunity +6

Myeloproliferative Neoplasia Remodels the Endosteal Bone Marrow Niche into a Self-Reinforcing Leukemic Niche

Koen Schepers, Eric M. Pietras, Damien Reynaud, +6

Cell stem cell

Hematological MalignancyTumor BiologyMixed-phenotype Acute LeukemiaHematologyPathology +8

FOXO3A directs a protective autophagy program in haematopoietic stem cells

Matthew R. Warr, Mikhail Binnewies, Johanna Flach, +5

Nature

Cell AutophagyMitophagyMedicineHematologyAutophagy +9

IL-6 Controls Leukemic Multipotent Progenitor Cell Fate and Contributes to Chronic Myelogenous Leukemia Development

Damien Reynaud, Eric M. Pietras, Keegan Barry-Holson, +6

Cancer Cell

Hematological MalignancyMixed-phenotype Acute LeukemiaImmunologyHematologyMedicine +4

Targeting TREM2 on tumor-associated macrophages enhances immunotherapy

Mikhail Binnewies, Joshua L. Pollack, Joshua Rudolph, +20

Cell Reports

Re-entry into quiescence protects hematopoietic stem cells from the killing effect of chronic exposure to type I interferons

Eric M. Pietras, Ranjani Lakshminarasimhan, José‐Marc Techner, +4

The Journal of Experimental Medicine

Adult Stem CellImmunologyCell DeathCell ProliferationCell Cycle +15

Visualizing Synaptic Transfer of Tumor Antigens among Dendritic Cells

Megan K. Ruhland, Edward W. Roberts, En Cai, +6

Cancer Cell