Myeloproliferative Neoplasia Remodels the Endosteal Bone Marrow Niche into a Self-Reinforcing Leukemic Niche

Koen Schepers, Eric M. Pietras, Damien Reynaud, +6

Cell stem cell

Hematological MalignancyTumor BiologyMixed-phenotype Acute LeukemiaHematologyPathology +8

Invasive breast cancer reprograms early myeloid differentiation in the bone marrow to generate immunosuppressive neutrophils

Amy-Jo Casbon, Damien Reynaud, Chanhyuk Park, +5

Proceedings of the National Academy of Sciences

One naive T cell, multiple fates in CD8+ T cell differentiation

Carmen Gerlach, Jeroen W. J. van Heijst, Erwin Swart, +7

The Journal of Experimental Medicine

Lymphocyte DevelopmentAdaptive Immune SystemImmunologyAntigen ProcessingImmune System +17

Tumor Rejection Induced by CD70-mediated Quantitative and Qualitative Effects on Effector CD8+ T Cell Formation

Ramon Arens, Koen Schepers, Martijn A. Nolte, +4

The Journal of Experimental Medicine

Recruitment of Antigen-Specific CD8 ⁺ T Cells in Response to Infection Is Markedly Efficient

Jeroen W. J. van Heijst, Carmen Gerlach, Erwin Swart, +7

Science

Adaptive Immune SystemT-regulatory CellNaïve T CellsImmunologyImmune Regulation +17

JunB Protects against Myeloid Malignancies by Limiting Hematopoietic Stem Cell Proliferation and Differentiation without Affecting Self-Renewal

Marianne Santaguida, Koen Schepers, Bryan King, +5

Cancer Cell

Affecting Self-renewalHematological MalignancyMedicineStem Cell MobilizationMyeloid Malignancies +11

Dissecting T cell lineage relationships by cellular barcoding

Koen Schepers, Erwin Swart, Jeroen W. J. van Heijst, +8

The Journal of Experimental Medicine

T Cells DisperseImmunogeneticsLineage PlasticityFunctional GenomicsCell Lineage +13

HIF signaling in osteoblast-lineage cells promotes systemic breast cancer growth and metastasis in mice

Claire-Sophie Devignes, Yetki Aslan, Audrey Brenot, +7

Proceedings of the National Academy of Sciences

Differential Kinetics of Antigen-Specific CD4+ and CD8+ T Cell Responses in the Regression of Retrovirus-Induced Sarcomas

Koen Schepers, Mireille Toebes, Gitte Sotthewes, +5

The Journal of Immunology

Adaptive Immune SystemT-regulatory CellImmunologyImmunodominanceImmune Control +17

Autophagy Proteins ATG5 and ATG7 Are Essential for the Maintenance of Human CD34+ Hematopoietic Stem-Progenitor Cells

Maria Catalina Gomez‐Puerto, Hendrik Folkerts, Albertus T.J. Wierenga, +4

Stem Cells