Phytochemical diversity of Clinacanthus nutans extracts and their bioactivity correlations elucidated by NMR based metabolomics

Leng Wei Khoo, Ahmed Mediani, Nur Khaleeda Zulaikha Zolkeflee, +5

Phytochemistry Letters

BiochemistryMedicineNutraceutical IngredientBioanalysisPhytochemical Diversity +7

Cephalomannine inhibits hypoxia-induced cellular function via the suppression of APEX1/HIF-1α interaction in lung cancer

Asmat Ullah, Sze Wei Leong, Jingjing Wang, +5

Cell Death and Disease

Lung InflammationCell DeathCancer BiologyTumor BiologyOxidative Stress +15

Synthesis and Sar Study of Diarylpentanoid Analogues as New Anti-Inflammatory Agents

Sze Wei Leong, Siti Munirah Mohd Faudzi, Faridah Abas, +8

Molecules

Induction of cell cycle arrest and apoptosis by copper complex Cu(SBCM)₂ towards oestrogen-receptor positive MCF-7 breast cancer cells

Jhi Biau Foo, Li Shan Ng, Ji Hui Lim, +10

RSC Advances

Synthesis of unsymmetrical monocarbonyl curcumin analogues with potent inhibition on prostaglandin E2 production in LPS-induced murine and human macrophages cell lines

Mohd Fadhlizil Fasihi Mohd Aluwi, Kamal Rullah, Bohari M. Yamin, +10

Bioorganic & Medicinal Chemistry Letters

InflammationMedicinal ChemistryAnti-inflammatoryChemoprevention StrategyBiochemistry +9

Nitric oxide inhibitory activity and antioxidant evaluations of 2-benzoyl-6-benzylidenecyclohexanone analogs, a novel series of curcuminoid and diarylpentanoid derivatives

Sze Wei Leong, Siti Munirah Mohd Faudzi, Faridah Abas, +8

Bioorganic & Medicinal Chemistry Letters

Antioxidant Evaluations2-Benzoyl-6-benzylidenecyclohexanone AnalogsDiarylpentanoid DerivativesOrganic ChemistryPharmacology +1

α-Glucosidase Inhibitory and Antioxidant Activities of Different<i>Ipomoea aquatica</i>Cultivars and LC-MS/MS Profiling of the Active Cultivar

Umar Lawal, Sze Wei Leong, Khozirah Shaari, +3

Journal of Food Biochemistry

α-Glucosidase InhibitoryPolyphenolicsOxidative StressFood ChemistryBioanalysis +14

Synthesis, biological evaluation and QSAR studies of diarylpentanoid analogues as potential nitric oxideinhibitors

Siti Munirah Mohd Faudzi, Sze Wei Leong, Faridah Abas, +7

MedChemComm

Combinatorial ChemistryPotential Nitric OxideinhibitorsBioorganic ChemistryOrganic ChemistryChemistry +16

Development of diarylpentadienone analogues as alpha-glucosidase inhibitor: Synthesis, in vitro biological and in vivo toxicity evaluations, and molecular docking analysis

Maryam Aisyah Abdullah, Yu‐Ri Lee, Siti Nurulhuda Mastuki, +7

Bioorganic Chemistry

Medicinal ChemistryPolyphenolicsBioorganic ChemistryBiochemistryDiarylpentadienone Analogues +7

Suppression of PGE2 production via disruption of MAPK phosphorylation by unsymmetrical dicarbonyl curcumin derivatives

Mohd Fadhlizil Fasihi Mohd Aluwi, Kamal Rullah, Md. Areeful Haque, +10

Medicinal Chemistry Research

Pge2 ProductionSignal TransductionBiochemistryMolecular RegulationMapk Phosphorylation +6