Concepedia

Induction of cell cycle arrest and apoptosis by copper complex Cu(SBCM)<sub>2</sub> towards oestrogen-receptor positive MCF-7 breast cancer cells

Jhi Biau Foo, Li Shan Ng, Ji Hui Lim, Pau Xien Tan, Yan Zhi Lor, Jason Siau Ee Loo, May Lee Low, Lee Chin Chan, Chaw Yee Beh, Sze Wei Leong,

RSC Advances · 2019 · 55 citations · 24 references

DOIFull text

Open access

Concepts

Abstract

Cu(SBCM)<sub>2</sub> binds to DNA topoisomerase I, which, in turn, induces cell cycle arrest and apoptosis in MCF-7 breast cancer cells, possibly <italic>via</italic> p53 signalling pathway.

References

24

Evaluation of Factors Related to Late Recurrence - Later than 10 Years after the Initial Treatment - in Primary Breast Cancer

Reiki Nishimura, Tomofumi Osako, Yasuyuki Nishiyama et al. · Oncology · 2013 · 13.2K citations · Full text

, , +17

Glide:  A New Approach for Rapid, Accurate Docking and Scoring. 1. Method and Assessment of Docking Accuracy

Richard A. Friesner, Jay L. Banks, Robert B. Murphy et al. · Journal of Medicinal Chemistry · 2004 · 9.9K citations

, , +17

A hierarchical approach to all‐atom protein loop prediction

Matthew P. Jacobson, David L. Pincus, Chaya S. Rapp et al. · Proteins Structure Function and Bioinformatics · 2004 · 2.5K citations

, , +17

Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of oestrogen receptor-positive breast cancer: ATLAS, a randomised trial

Christina Davies, Hongchao Pan, Jon Godwin et al. · The Lancet · 2012 · 2K citations · Full text

, , +14

Novel Procedure for Modeling Ligand/Receptor Induced Fit Effects

Woody Sherman, Tyler Day, Matthew P. Jacobson et al. · Journal of Medicinal Chemistry · 2005 · 2K citations

, , +16