Blood-based tumor mutational burden as a predictor of clinical benefit in non-small-cell lung cancer patients treated with atezolizumab

David R. Gandara, Sarah Paul, Marcin Kowanetz, +19

Nature Medicine

OncologyPathologyBronchial NeoplasmClinical BenefitCancer Genetics +3

Quantitative visualization of alternative exon expression from RNA-seq data

Yarden Katz, Eric T. Wang, Jacob Silterra, +7

Bioinformatics

Proteomics, Post-translational Modifications, and Integrative Analyses Reveal Molecular Heterogeneity within Medulloblastoma Subgroups

Tenley C. Archer, Tobias Ehrenberger, Filip Mundt, +28

Cancer Cell

Systems BiologyFunctional GenomicsTumor HeterogeneityPost-translational ModificationsGenetics +10

Responses to Bacteria, Virus, and Malaria Distinguish the Etiology of Pediatric Clinical Pneumonia

Clarissa Valim, Rushdy Ahmad, Miguel Lanaspa, +15

American Journal of Respiratory and Critical Care Medicine

A genomic and evolutionary approach reveals non-genetic drug resistance in malaria

Jonathan D. Herman, Daniel P. Rice, Ulf Ribacke, +9

Genome biology

Abstract 5706: A blood-based next-generation sequencing assay to determine tumor mutational burden (bTMB) is associated with benefit to an anti-PD-L1 inhibitor, atezolizumab

David Fabrizio, Daniel S. Lieber, Christine M. Malboeuf, +15

Cancer Research

ImmunologyPathologyImmunotherapyHematological MalignancyOncology +14

A genomic and evolutionary approach reveals non-genetic drug resistance in malaria

Jonathan D. Herman, Daniel P. Rice, Ulf Ribacke, +9

Genome Biology

Cprs GenePlasmodium FalciparumNatural SciencesGeneticsEvolutionary Biology +11

Analytic validation of a next generation sequencing assay to identify tumor mutational burden from blood (bTMB) to support investigation of an anti-PD-L1 agent, atezolizumab, in a first line non-small cell lung cancer trial (BFAST)

David Fabrizio, Christine M. Malboeuf, Daniel S. Lieber, +17

Annals of Oncology

Next GenerationTumor Mutational BurdenMedicineMetronomic TherapyImmunology +7

Transcriptional categorization of the etiology of pneumonia syndrome in pediatric patients in malaria endemic areas

Jacob Silterra, Michael A. Gillette, Miguel Lanaspa, +14

The Journal of Infectious Diseases

A compact soft X-ray microscope using an electrode-less Z-pinch source

Stephen F. Horne, Jacob Silterra, W. M. Holber

Journal of Physics Conference Series

X-ray SpectroscopyEngineeringMicroscopyBiomedical EngineeringPolycapillary Optics +16