Nature Medicine · 2018 · 1.2K citations · 32 references
MedicineOncologyPharmacologyCancer GeneticsMedical OncologyMolecular OncologyCancer ImmunotherapyCancer PharmacogenomicsChemotherapy PharmacogenomicsLung Cancer PharmacotherapyMalignant NeoplasmsOncogene MutationsAtezolizumab TherapyNon-small Cell Lung Cancer TherapyNon-small Cell Lung Cancer TreatmentTumor Mutation Burden AssessmentTumor Mutation Burden BiomarkersTumor Mutational BurdenTumor Mutational Burden Assessment
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Signatures of mutational processes in human cancer
Ludmil B. Alexandrov, Serena Nik‐Zainal, David C. Wedge et al. · Nature · 2013 · 10.1K citations · Full text
Medicine, Cancer Biology, Oncology +14
Pembrolizumab versus Chemotherapy for PD-L1–Positive Non–Small-Cell Lung Cancer
Martin Reck, Delvys Rodríguez‐Abreu, Andrew Robinson et al. · New England Journal of Medicine · 2016 · 10.1K citations · Full text
Medicine, Oncology, Pharmacology +17
Nivolumab versus Docetaxel in Advanced Nonsquamous Non–Small-Cell Lung Cancer
H. Borghaei, L. Paz-Ares, Leora Horn et al. · New England Journal of Medicine · 2015 · 9.5K citations · Full text
Nivolumab versus Docetaxel in Advanced Squamous-Cell Non–Small-Cell Lung Cancer
Julie R. Brahmer, Karen L. Reckamp, Lucio Crinò et al. · New England Journal of Medicine · 2015 · 8.6K citations · Full text
Pharmacy, Oncology, Pharmacotherapy +15
Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer
Naiyer A. Rizvi, Matthew D. Hellmann, Alexandra Snyder et al. · Science · 2015 · 7.9K citations
Medicine, Immunology, Oncology +17